The Baltimore Museum of Art (BMA) is set to unveil its newly renovated wing this month - the first phase of its US$24.5m (£15.4m, 19.2m euro) revamp.
Renovations to the wing include 16 galleries showcasing masterworks by Robert Rauschenberg and Andy Warhol.
A range of new acquisitions and emerging artists will also be on display including The Shallow Sea, a sound installation by Turner Prize-winning artist Susan Philipsz.
The wing will also feature an architectural intervention by New York-based artist Sarah Oppenheimer. The two-part work involved the artist cutting through the wall between the contemporary and Cone wings to connect periods of art using mirrored and aluminium sculptural forms.
Other renovations include three new exhibitions, two interactive galleries and a new black box gallery for light, sound and moving image.
In addition to the revamped wing, the BMA's US$24.5m investment includes the reinstallation of its American and African collections, and improvements to the lobby. The project is expected to be fully complete by 2014.
Museum director Doreen Bolger said: "We look forward to welcoming our visitors into a transformed environment that will create thought-provoking encounters with contemporary art."
BMA currently has 90,000 works of art - including the largest holding of works by Henri Matisse.